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What (who) is BRCA2 - definition
BRCA2
![5’-3’]].](https://commons.wikimedia.org/wiki/Special:FilePath/Mutação dos genes BRCA1 e BRCA2 de portadoras de câncer de mama.png?width=200 "5’-3’]].")
BRCA2 (em inglês, breast cancer 2) é um gene supressor de tumor e, assim como BRCA1, a identificação de mutações nesse gene é relevante para o diagnóstico de predisposição ao câncer de mama e ovário. Mutações nesse gene também conferem risco aumentado para o muitos outros tipos de câncer, incluindo câncer de mama em homens, câncer de pâncreas e câncer de próstata.
Examples of use of BRCA2
1. Their latest tests revealed that the two compounds they studied both acted on BRCA1 and BRCA2.
2. Fewer than five per cent of all breast cancers are due to BRCA1 and BRCA2 genes.
3. Most are due to mutations in the BRCA1 or BRCA2 genes.
4. Carriers of the BRCA1 and BRCA2 genes will be given high–tech MRI scans from the age of 30.
5. The spectrum of BRCA1 and BRCA2 mutations was "vastly different" between families of African and European ancestry.